There is no one “best” Photoshop setting for print, as different printers produce different results. However, some general tips to help improve print prints include using a large color space (e.g. sRGB), using a smooth or even texture on paper, and avoiding banding or noise.
There is no one definitive answer to this question. Some Photoshop tips that may help include using the “print” command to print out a document of your desired size, using the “fit to page” feature to size the document so it will fit on a page in your printer, and using the “fit to width” feature to size the document so it will fit on a width-matched printer paper.
CMYK is a color space that uses the colors cyan, magenta, yellow, and black.